Anti glaucoma Drugs Commonly Used

The Most Common Anti glaucoma Drugs

Brand Names: Alphagan P
Therapeutic Category: Ophthalmic Agent, Anti glaucoma Drugs
Dosage Forms: Solution, Ophthalmic
Use: Labeled Indications: Elevated intraocular pressure: Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
Ocular redness (OTC only): Relief of redness of the eye due to minor eye irritations
Dosing : Adult Instill 1 drop in affected eye(s) 3 times/day (approximately every 8 hours)
Dose Adjustments
Renal Impairment:. no dosage adjustments
Hepatic Impairment: No dosage adjustment.
Adverse Drug Interaction:
Drowsiness, Allergic conjunctivitis, conjunctival hyperemia, eye pruritus, Dizziness, fatigue, foreign body sensation of eye, headache
Pharmacodynamics/Kinetics:
Metabolism: Hepatic
Half-life elimination: 3 hours
Time to peak, plasma: 1 to 4 hours
Excretion: Urine
Important Notes:
May cause CNS depression, which may impair physical or mental abilities; patients must be cautioned about performing tasks which require mental alertness
Pregnancy & Lactation: Pregnancy Risk Factor B / not known if brimonidine is excreted in breast milk.
Drug safety issue:

Brimonidine may be confused with bromocriptine

Brand Names: Xalatan
Therapeutic Category: Ophthalmic Agent, Anti glaucoma Drugs
Dosage Forms: Solution, Ophthalmic
Use: Labeled Indications: Elevated intraocular pressure: Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma and ocular hypertension.
Dosing : Adult :One drop in the affected eye(s) once daily in the evening
Dose Adjustments
Renal Impairment:. no dosage adjustments
Hepatic Impairment: No dosage adjustment.
Adverse Drug Interaction:
Foreign body sensation of eye, Eye pain , stinging of eyes ,ocular hyperemia ,conjunctival hyperemia ,eye discharge , increased eyelash length, hyperpigmentation of eyelashes
Pharmacodynamics/Kinetics:
Onset of action: 3 to 4 hours
Peak effect: Maximum: 8 to 12 hours
Half-life elimination: 17 minutes
Metabolism: Primarily hepatic
Important Notes:
May change/increase brown pigmentation of the iris, the eyelid skin, and eyelashes; length and/or number of eyelashes may also be increased.
Pregnancy & Lactation: Pregnancy Risk Factor C / not known if present in breast milk.
Drug safety issue:

Latanoprost may be confused with Lantus

Xalatan may be confused with Lantus, Travatan, Xalacom, Zarontin

Brand Names: Betimol
Therapeutic Category: Ophthalmic Agent, Anti glaucoma Drugs
Dosage Forms: Solution, Ophthalmic
Use: Labeled Indications: Elevated intraocular pressure: Treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma
Dosing : Adult Instill 1 drop (0.5% solution) once daily in the morning
Dose Adjustments
Renal Impairment:. no dosage adjustments
Hepatic Impairment: No dosage adjustment.
Adverse Drug Interaction:
Burning sensation of eyes, stinging of eyes, Angina pectoris, bradycardia, cardiac arrhythmia, cardiac failure, cerebral ischemia, cerebrovascular accident, claudication, cold extremities, edema, heart block, hypertension, hypotension, palpitations, Raynaud’s phenomenon
Pharmacodynamics/Kinetics:
Onset of action: Intraocular pressure reduction: 30 minutes
Peak effect: 1 to 2 hours
Duration: 24 hours
Half-life elimination: 4 hours
Important Notes:
Patient may experience burning, common cold symptoms, or stinging. Have patient report immediately to prescriber signs of severe cerebrovascular disease (difficulty speaking or thinking, change in balance, or vision changes
Pregnancy & Lactation: Pregnancy Risk Factor C / present in breast milk
Drug safety issue:

Timolol may be confused with atenolol, Tylenol

Timoptic may be confused with Betoptic S, Talacen, Viroptic

Anti glaucoma Drugs