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Read & Download your Issue of Thursday – February 18 FNN News
Peptidic vaccines: The new cure for heart diseases?
- Cardiovascular disease continues to be the most common cause of death worldwide.
- This review focuses on peptidic vaccines, with the known and not well-known autoantigens in atheroma formation or acquired cardiac diseases, as novel potential immunotherapy approaches to counteract harmful heart disease continuance.
- They summarize how cancer immunomodulatory strategies started novel approaches to modulate the innate and adaptive immune responses, and how they can be targeted for therapeutic purposes in the cardiovascular system.
Source: ScienceDirect
Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy
- Lupeol is a natural triterpenoid that widely exists in edible fruits and vegetables, and medicinal plants.
- This review aims to summarize the advances in pharmacological and pharmacokinetic studies of lupeol in the last decade with an emphasis on its anticancer and anti-inflammatory activities, as well as the research progress of lupeol derivatives thus far, to provide researchers with the latest information, point out the limitations of relevant research at the current stage and the aspects that should be strengthened in future research.
Source: ScienceDirect
Dendritic cell vaccine therapy for colorectal cancer
- Colorectal cancer (CRC) remains a leading cause of cancer-related deaths in the United States despite an array of available treatment options.
- Current standard-of-care interventions for this malignancy include surgical resection, chemotherapy, and targeted therapies depending on the disease stage.
- Specifically, infusion of anti-vascular endothelial growth factor agents in combination with chemotherapy was an important development in improving the survival of patients with advanced colorectal cancer.
Source: ScienceDirect
Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder
- Depression is a common global mental disorder that seriously harms human physical and mental health.
- Here, they summarized the anti-depressant natural volatile oils and their monomers from herbal medicine, discussed the anti-depressive mechanisms of the volatile oils from natural medicine.
- This review would be helpful for the development of potential anti-depressant medicine and provide new alternative treatments for depressive disorders.
Source: ScienceDirect
Ā Mechanisms of action of metformin and its regulatory effect on microRNAs related to angiogenesis
- Angiogenesis is rapidly initiated in response to pathological conditions and is a key target for pharmaceutical intervention in various malignancies.
- Anti-angiogenic therapy has emerged as a potential and effective therapeutic strategy for treating cancer and cardiovascular-related diseases.
- This paper reviews the drugātarget interactions and drug repositioning events of metformin that influences vascular cells and has benefits on angiogenesis-mediated effects.
Source: ScienceDirect
The effects of chromium supplementation on lipidprofile in humans: A systematic review and meta-analysis ofrandomized controlled trials
- This systematic review and meta-analysis aimed to evaluate the effects of chromium supplementation on lipid profile.
- Thirty-eight studies comprising 41 treatment arms and 7605 participants included to the present meta-analysis.
- This meta-analysis reveals that there was only an overall significant association between chromium supplementation with decreases in the concentration of TC.
Source: ScienceDirect
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FADIC 2021 Pharmacotherapy Daily News
(FNN)
Directed By/ Rasha Abdelsalam
FADIC Pharmacy’s Daily Newspaper works like this:
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