2- Tuesday  Pharmacy Practice News – 23th March

1 – Surveillance testing reveals a significant proportion of hospitalized patients with SARS-CoV-2 are asymptomatic

• The proportion of positive patients admitted to acute-care hospitals for reasons other than coronavirus disease-19 (COVID-19) is unknown. These patients potentially put other patients and healthcare workers at risk of infection.
• The objective of this study was to define the proportion of asymptomatic patients admitted with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).
• Secondary objectives were to define the positivity rate, reasons for admission, and the geographic distribution in the region.

Source: ScienceDirect

2 – 3D printing of face shields to meet the immediate need for PPE in an anesthesiology department during the COVID-19 pandemic

• Anesthesia providers are at risk for contracting COVID-19 due to close patient contact, especially during shortages of personal protective equipment.
• This study presents an easy to follow and detailed protocol for producing 3D printed face shields and an effective decontamination protocol, allowing their reuse.
• This protocol enabled the rapid production of face shields by individuals with little to no 3D printing experience, and provided a simple and effective decontamination protocol allowing reuse of the face shields.

Source: ScienceDirect

3 – What are the sources of exposure in healthcare personnel with coronavirus disease 2019 infection?

• Healthcare personnel are at risk for nosocomial acquisition of COVID-19.
• This study evaluated the exposure history of hospital personnel with COVID-19.
• Twenty-five percent of personnel with COVID-19 were exposed to an infected patient or co-worker.
• Exposure to infected co-workers occurred in nonpatient care settings.
• Fourteen percent of personnel with COVID-19 were exposed in the community.

Source: ScienceDirect

4- Novel outpatient antibiotic prescribing report of respiratory infections in a pediatric health system’s emergency departments and urgent care clinics

• A novel antibiotic tracking report for respiratory infections in a pediatric acute care network was created.
• Encounters were analyzed without competing diagnoses to determine appropriateness of therapy.
• Low antibiotic use was indentified for infections where systemic antibiotics are not recommended.
• They report high first-line antibiotic use for respiratory infections where antibiotics are typically recommended.
• Site- and diagnosis-specific variabilities require tailored antibiotic stewardship approaches.

Source: ScienceDirect

5 – Inactivation of SARS-CoV-2 by commercially available alcohol-based hand sanitizers

• Alcohol solutions and WHO alcohol-based liquid sanitizer formulations have demonstrated efficacy against the COVID-19 associated SARS-CoV-2 virus in previous publications.
• Two formulated alcohol-based hand sanitizers, a gel and a foam each containing 70% ethanol, yielded complete reduction of SARS-CoV-2, with >3 log10 reductions, in suspension testing with a 30 second contact time.
• Further research is warranted on the efficacy of alcohol-based hand sanitizers against coronaviruses on the hands and understanding the impacts of hand hygiene on transmission of COVID-19.

Source: ScienceDirect

6 – Behavior change techniques to promote healthcare professionals’ eHealth competency: A systematic review of interventions

• The use of eHealth is rapidly increasing; however, many healthcare professionals have insufficient eHealth competency.
• Consequently, interventions addressing eHealth competency might be useful in fostering the effective use of eHealth.
• This systematic review aimed to identify and evaluate the behavior change techniques applied in interventions to promote healthcare professionals’ eHealth competency.

Source: ScienceDirect

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