5- Friday Nutrition News – 1st October

pro-inflammatory diet and mortality in hemodialysis patients

• A  cohort study aim to evaluate the interrelationships between dietary, nutritional, and inflammatory factors in predicting all-cause mortality among individuals in hemodialysis (HD) treatment.
• Sociodemographic, anthropometric, and clinical data were collected. Dietary inflammatory index (DII®) scores were calculated from a quantitative food frequency questionnaire. Data were analyzed by path analysis.
• The results conclude that  More pro-inflammatory diet and systemic inflammation have a direct association with mortality among subjects under HD therapy.

Source: Elsevier journal

High fat diet and ACE2

• A study aim to evaluate the impact of a high-fat diet (HFD) and maternal HFD on the intestinal ACE2 levels in adults and neonates. The study examined intestinal ACE2 protein levels in mice with diet-induced obesity and neonatal mice exposed to a maternal high-fat diet.
• The results indicate that Intestinal ACE2 protein levels are increased in mice with high-fat diet-induced obesity. Also, Maternal high-fat diet feeding decreases intestinal ACE2 levels in the offspring compared with normal diet feeding.

Source: Elsevier journal

Phase angle as a biomarker

• A Cross- sectional study aim to assess the association of phase angle (PhA) with metabolic profile in adults of both sexes.
• The PhA was measured based on electrical bioimpedance analysis (BIA).
• The results indicate that Lower PhA is positively associated with waist circumference, glucose, non-HDL-C, triglycerides, PCR, HOMA-IR and uric acid. Also, Lower PhA is inversely associated with HDL-C. this outcome suggests that PhA is a promising cardiometabolic profile biomarker in adults.

Source: Elsevier journal

Flavonoids and ESCC

• A study aim to investigate the association between dietary consumption of the total, subclasses, and specific flavonoids and the risk of esophageal squamous cell carcinoma (ESCC) among adults in a high-risk area of China.
• The results suggest that increased dietary intake of isoflavones and moderate consumption of anthocyanidins were associated with a decreased risk of ESCC.
• Future nutritional guidelines may emphasize foods or supplements rich in specific isoflavones and anthocyanidins for ESCC chemoprevention.

Source: Elsevier journal

Eucaloric ketogenic diet and COVID-19

• A study objective is to explore the effect of Eucaloric ketogenic diet (EKD) on mortality, admission to intensive care unit (ICU) and the need for non-invasive ventilation in hospitalized patients affected by COVID-19 .The results found a possible therapeutic role of EKD in the clinical management of COVID-19.
• EKD seems to have a role in modulate inflammatory markers in particular on IL-6. Further studies are mandatory to clarify the role of ketogenic nutrition in Covid-19.

Source: Elsevier journal

Vitamin D and OSA

• A study aim to assess the significance of vitamin D and PTH, VDR, and PTH gene polymorphisms with body composition and biochemical investigations in Asian Indians with obstructive sleep apnea(OSA )and without OSA.
• Clinical, body composition, anthropometry, biochemical investigations, and full overnight polysomnography were measured.
• The results show that Lower serum 25(OH) D levels were significantly observed in OSA and correlate with disease severity. Also, VDR and PTH mutations were found highly related to OSA in Asian Indians.

Source: Elsevier journal

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