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Get Privacy Trending: Best Practices for the Social Media Educator

• Social media is an increasingly popular forum for medical education.
• Many educators, including those in infectious diseases, are now creating and sharing unique and educational patient cases online.
• Unfortunately, some educators unknowingly threaten patient privacy and open themselves to legal liability.
• This summary will define the legal requirements of patient de-identification as well as other practical recommendations as it relates to use of clinical case information, patient images, and attribution of primary references on social media.

Source: Oxford Academic

Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19

• Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people and caused 1.48 million deaths, just 12 months from the first diagnosis.
• This review presents several lines of evidence, which suggest curcumin as a promising prophylactic, therapeutic candidate for COVID-19.

Source: ScienceDirect

A systematic review of clinical and laboratory parameters associated with increased severity among COVID-19 patients

• Corona virus disease 2019 (COVID-19) has been an extremely difficult pandemic to contain.
• The main aim of this systematic review is to provide a comprehensive summary of clinical and laboratory parameters that are associated with and indicative of increased severity among COVID-19 patients.
• This systematic review suggests that COVID-19 is a disease with varied clinical presentation and laboratory parameters.
• The commonest clinical symptoms were fever, cough and dyspnea. The laboratory parameters associated with severe disease were lymphopenia, elevated LDH, D dimer and Procalcitonin.

Source: ScienceDirect

Frequency of Atrial Arrhythmia in Hospitalized Patients with COVID-19

• There is growing evidence that COVID-19 can cause cardiovascular complications.
• However, there are limited data on the characteristics and importance of atrial arrhythmia (AA) in patients hospitalized with COVID-19.
• Patients diagnosed with AA had 3.1 times significant increase in mortality rate versus patients without diagnosis of AA in COVID-19 patients.
• Data from 1029 patients diagnosed with of COVID-19 between March 1st and April 15th 2020 were analyzed.
• Older age, male gender, azithromycin use and higher baseline D-dimer levels were predictors of mortality.

Source: ScienceDirect

Recent knowledge in favor of remdesivir (GS-5734) as a therapeutic option for the COVID-19 infections

• The management of SARS-CoV-2 has not yet been clearly determined and is based on potential therapies evaluated during the SARS-CoV and MERS-CoV outbreaks.
• An emerging potential therapeutic approach currently being evaluated in numerous clinical trials is the remdesivir agent, which acts on COVID-19 by interfering with key steps in the virus replication cycle.
• In this work, we provide an overview of remdesivir’s discovery, mechanism of action, and the current studies exploring its clinical effectiveness. Recommendations for its use against COVID-19 infection are also summarized.

Source: ScienceDirect

Progesterone in Addition to Standard of Care Versus Standard of Care Alone in the Treatment of Men Hospitalized with Moderate to Severe COVID-19: A Randomized, Controlled Pilot Trial

• Severity of illness in COVID-19 is consistently lower in women. Focus on sex as a biologic factor may suggest a potential therapeutic intervention for this disease.
• They assessed whether adding progesterone to standard of care would improve clinical outcomes of hospitalized men with moderate to severe COVID-19.
• Progesterone at a dose of 100 mg, twice daily by subcutaneous injection in addition to SOC may represent a safe and effective approach for treatment in hypoxemic men with moderate to severe COVID-19.

Source: ScienceDirect

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